Unfortunately for us Vito's anxiety has actually increased while on Clomipramine. He has been on it for 25days and was on Alprazolam (Xanax) for 17days but that was having zero effect.
Vito's appetite has also decreased and he wasn't that food motivated to begin with. We were supposed to start feeding him out of food dispensing toys and leaving him alone while eating. In theory the food toys would require more engagement and keep his brain busier than just chewing on bones. Well Vito has zero interest in eating his stuffed kongs while crated at work even though he can see me. Often he has zero interest period. He likes his orange food ball but at times will just push it around and ignore the kibble falling out. The Kong Wobbler is ok but insanely easy to get out food and again he's just not that interested. Vito likes the Tug a Jug the most but still not enough to eat when he doesn't want. During training sessions it is not uncommon for Vito to work for the click but refuse the actual food. Interestingly enough the harder I make what we are working on the more likely Vito is to actually eat the food as a reward. It's as though he thinks he really earned it so better eat it.
Vito has been sleeping a lot. I don't know if this is due to the medication or not since I was honestly worried about him before the medication started. Hard to say if he is sleeping more now or not. He certainly isn't bringing me toys and harassing me to play and I can't remember the last time he played tug with Chuckles.
To add to the other changes Vito has been even more reactive. He's reacting to people in situations that normally wouldn't cause any reaction. Typically Vito is only reactive in quiet settings when there is a big change in the environment. Loud dog shows rarely cause outbursts but a person walking into a quiet room and waving does trigger him. This past month Vito has reacted several times at the busy obedience club and to almost every person entering the building at work.
On the positive side, we have been resuming our SA protocal and have been doing several short departures that have all gone well. Most of our absences have been between 10-30min and during ALL Vito has chewed on his bones and has been completely relaxed. We have done 2 "long" departures of 55min and 75min and Vito was also fine during them.
I don't know if the goodness has been due to the medications or not as we had worked up to 2.5hrs absences at one point before he started getting worse this past August. The main difference these past trials is that Vito has been eating his bones everytime we leave them instead of just for 10 minutes. His longest time of chewing has still been 50minutes which is consistent with his highest time before the meds. He still has not slept while we were gone which would be HUGE for Vito but he hasn't really been left alone long enough to do so.
At work there has been zero change in anxiety level. I'm going to put it under the good category since he did not get worse at least :) Still doesn't want to go in his crate during my training of the other dogs, still stands at the baby gate the entire time he is penned up in my cubicle when I'm gone, but is still not whining.
Goodbye Clomipramine, hellox Prozac, and welcome back Xanax. At his recheck appointment today we decided that minimally Clomipramine is not helping Vito regardless of whether it is contributing to the other issues that have started. We are going to see if Fluoxetine (Prozac) will help him and re continue his Xanax at a higher dose.